الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the work: 1- Prevalence of Barrett’s esophagus in patients with GERD in EL-Minia university hospital. 2- Relation between H. pylori infection and GERD. 3- Relation between carditis and Barrett’s esophagus. 4- pH metry study in patients with GERD and Barrett’s esophagus. Occlusion: In the end, what really matters in the concept that GERD is a multifaceted clinical problem, and that a modern approach should focus on the symptoms rather than on the presence of a 5 mm mucosal break in the distal esophagus. The rigid division into three patient’s subgroups (NERD, erosive and Barrett’s) appears to limit rather than expand our concentration on symptoms. On the contrary, an annual progression rate from NERD to GERD is possibly as high as 30% and 13% the rate of annual Barrett’s esophagus development in GERD patients. A considerable number of patients with reflux oesophagitis have Barrett’s mucosa by histopathological examination without having salmon pink appearance endoscopically. There was slight difference between grading of oesophagitis endoscopically and histopathologically. There was low incidence of H. pylori with patients of Barrett’s esophagus. There was high correlation between Barrett’s esophagus and carditis. GERD is a progressive disease. This may have significant consequences for example the needed for periodic reassessment of disease severity and/ or the screening for Barrett’s esophagus throughout the patient’s life. |