الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the work To evaluate the presence or absence of a link between blood transfusions and lipid peroxidation as determined by urinary and serum Malondialdehyde (MDA) concentration in preterm infants. And if there is relation between blood transfusion and the incidence of occur retinopathy in preterm. Conclusion The study revealed that there is a statistically significant elevation of plasma and urine MDA in the post transfusion infants when compared with control group in different body weights or different gestational ages and the retinopathy of prematurely is also highly increased in post transfusion infants in different body weights and different gestational ages. The study recommended that it is advised to limit oxidative damage by giving fewer transfusions or by using more restrictive transfusion regimens, and recommended also that it is advised to use alternatively fresh whole blood, containing plasma antioxidants rather packed RBCs, to be given to preterm infants. The study recommends that screening of all preterm infants who are admitted to NICU should be done to early detect any signs suggestive of retinopathy of prematurity. |