الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the work: The aim of the work is to determine the level of anticardiolipin antibodies in patients with chronic liver disease and correlate its level with clinical features in those patients. Conclusions: Our study clearly revealed that aCL antibodies are one of the most common auto antibodies found in patients with chronic liver disease (mainly in chronic viral hepatitis). The prevalent concept is that, in the majority of cases, aCL antibodies are non pathogenic and therefore their routine determination is not justified. However, in particular patients with special immune reactivity or with abnormal haemostatic regulation, they may exert a pro-coagulant effect and be involved in the genesis of thrombotic events. Finally it remains unknown whether aCL antibodies and any HCV Antigen. Thus, the prevalence of aCL antibodies in our patients that was higher than in the normal controls had no clinical significance and so, as other auto antibodies described in conjunction with HCV infection, aCL antibodies seem mostly to be an epiphenomenom. |