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Abstract Obsessive compulsive disorder (OCD) is a chronic and often disabling anxiety disorder. It is characterized by recurrent unwanted intrusive thoughts (obsessions) and or engage in repetitive ritualistic behaviors (compulsion).Obsession include worries,doubts ,or images that evokes anxiety or distress and persist even though the patient recognizes the symptoms as irrational, ritualistic, untrue. Obsessive compulsive disorder is the fourth most frequent psychiatric condition following the phobias, substance abuse and major depression .The estimated lifetime prevalence of OCD in the United States was 2-3%. The course of OCD is moderately stable: longitudinal twin studies as well as epidemiological and clinical. Functional imaging studies have repeatedly reported the presence of brain abnormalities in obsessive-compulsive disorder (OCD), involving predominantly the orbitofrontal and anterior cingulate cortices, basal ganglia, and thalamus. |