الفهرس | Only 14 pages are availabe for public view |
Abstract The main objectives of the current study include: Firstly, examination the incidence of catheter-related bloodstream infection in surgical intensive care units at Emergency Hospital, Mansoura University. Secondly, identification of the leading pathogens causing clinically significant nosocomial bloodstream infection. Thirdly, determination of antibiotic sensitivity of the isolated organisms. Finally, analysis of risk factors associated with catheter related bloodstream infection. The leading pathogens causing clinically significant nosocomial bloodstream infection in our institution were Staphylococcus epidermidis (44%), Staphylococcus aureus (32%), Klebsiella pneumoniae (12%) and Pseudomonas aeruginosa (12%). Meanwhile, Enterococcus faecalis (3.3%) and E. coli (5%) were detected as catheter colonization in the 10th day. Vancomycin, meronem and ciprofloxacin were most potent towards all the gram-positive cocci. On the other hand, the isolated gram-negative bacilli were highly sensitive to amikacin and imipenem. Factors including age, total parenteral nutrition use, caliber of the inserting physician, maximal sterile precautions, site of insertion, number of central venous catheter lumens, colonization of the catheter and duration of catheterization were significantly associated with central venous catheter- related bloodstream infection in surgical intensive care units patients. Meanwhile, no significant difference was found for gender, primary diagnosis, place of insertion, frequency of dressing, and type of dressing. |