الفهرس | Only 14 pages are availabe for public view |
Abstract Imidocarb is 1, 3-bis [3-(4, 5-dihydro-lH-imidazol-2-yl) phenyl] urea. It is white or off white crystalline powder. It is soluble in water, methanol; moderately soluble in acids; slightly soluble in buffers at pH 8; practically insoluble in base and insoluble in non polar organic solvents such as acetone. Among a variety of drugs that has been advocated over the years as therapeutic or prophylactic agents against infection with hemoprotozoa in domestic animals, imidocarb (IMD) is considered the most efficacious and safest of all available medications (I). It is a chemotherapeutic agent with antiprotozoal activity. It is usually administered as dipropionate salt and has been used over 20 years in the treatment and prophylaxis of some protozoal diseases such as babesiosis (Malaria like infection) and anaplasmosis in food-producing species. It is administered to cattle as the dipropionate salt at approximately 3 mg kg-I body weight for the treatment of red water disease (2,3). |