الفهرس | Only 14 pages are availabe for public view |
Abstract Obesity is a major public epidemic health problem contributing to mortality and morbidity such as type 2 diabetes mellitus, coronary artery disease, hypertension, dyslipidemia, asthma, OSAS, GERD, stroke, cancer, joint disease and depression. Obesity is assessed by BMI however some advocate that waist-to-hip ratio is a more sensitive indicator for the degree of obesity and its co morbidities. Evolution of many bariatric surgical procedures unfolded over the last few decades. Some of these procedures are directed towards restriction of gastric volume and other are aiming at affecting the absorptive capacity of the gut. This study reviews the functional assessment of LSG and BIB on patients with morbid obesity. LSG involves a longitudinal resection of the stomach on the greater curvature from the antrum starting 2-6 cm proximal to the pylorus up to the angle of His. LSG is a multifactorial procedure. In addition to the mechanical restrictive effects, SG has hormonal effects. This operation is anorexigenic as the fundus is known to be the major source of ghrelin; the patients feel little hunger and have only a mild interest in eating. Other hormonal changes have been noted, such as a rise in the level of fasting PYY or GLP1, a hormone that induces also a feeling of satiety. |