الفهرس 
Pathology Solitary Thyroid NoduleOnly 14 pages are availabe for public view
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Abstract
Solitary thyroid nodule is a discrete swelling in one lobe with no palpable abnormality elsewhere. Thyroid nodules are discovered in 4% to7% of the population by palpation.
Solitary thyroid nodules are most commonly because of benign conditions and malignant neoplastic nodules include those of thyroid origin and metastatic disease from other primary tumors.
The initial investigation required in all patients with a clinical solitary nodule is a biochemical assessment of thyroid function including (TSH) assay, thyroglobulin assay, calcitonin assay and molecular markers.
The use of ultrasound in the evaluation of patients with thyroid lesions has expanded from routine detection of non-palpable thyroid nodules to include the delineation of benign and malignant lesions, the examination of lymph node, FNA guidance. The most important useful further investigation is the fine needle aspiration biopsy and pathological examination of the specimen.
Clinical management of thyroid nodules should be guided by the results of ultrasound evaluation and FNA biopsy. Thyroid nodules may be classified into the following five classes: non diagnostic, benign, follicular lesion, suspicious for malignancy and malignant.