الفهرس 
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Abstract
Hepatocellular carcinoma is the most common primary hepatic
malignancy, representing more than 90% of primary liver neoplasms. Its
incidence is high in Africa and Asia and has substantially increased
worldwide during the past three decades. The majority of HCC (8090%)
are associated with underlying liver disease related to post-hepatitis
cirrhosis, or alcohol abuse.
LT is in theory the optimal treatment of HCC, the triple advantage to
remove the tumor, to prevent the possibility of metachronous lesions on
underlying cirrhosis and to restore normal liver function. Accordingly, a
great enthusiasm was faced with liver transplantation in the eighties.
However, high recurrence rates and poor outcomes were recorded from the
first series of transplanted patients. These poor results were mostly related to
unrestrictive selection criteria, inclusion of patients with macroscopic
vascular invasion, lymph node involvement and extrahepatic spread.
Nowadays, LT has reached its phase of maturity with a better knowledge of
the prognostic factors.
The aim of this work is to study the outcome of living donor liver
transplantation for HCC patients by evaluation of; adequacy and accuracy of
different diagnostic tools for HCC, the different controversies related to
selection criteria and bridging, specific preoperative, operative and
postoperative difficulties, and predictors and management of recurrence, in
the cases done in the National Liver Institute, Menoufiya University.