الفهرس 
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Abstract
Lactate concentration is reported to be high in amniotic fluid (AF). Preterm prelabour rupture of membranes (PPROM) is defined as rupture of the fetal membranes prior to onset of labour in patients who has gestational age of less than 37 weeks. It occurs in about 3-5% of all pregnancies. The condition is associated with fetal and maternal complications, and might be a marker of imminent delivery, therefore among women with suspected (PPROM); it is of a great importance to accurately confirm the diagnosis.
In this study we try to assess whether lactate determination in vaginal fluid could be used as a diagnostic test for PPROM.
A lactate concentration > 4.4 mmol/L was found to be the best cut-off value for a positive ”lac-test” and show a sensitivity of 96.3% and specificity 84.8%.
This thesis show the usefulness of determination of lactate in AF, which can be used in prediction of PPROM.