الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of this study was to correlate the ankle-brachial index value (low, border line normal or high) with coronary calcification measured by coronary calcium score. This study was conducted at Ain Shams University Specialized hospital and enrolled 100 patients undergoing MDCT scan. All patients were subjected to the following: 1) Careful history analysis. 2) Full clinical examination. 3) The ankle-brachial index was calculated with the duplex probe placed over the brachial and dorsalis pedis or posterior tibial artery, and Patients categorized according to ankle-brachial values into: a- low ABI: (< 0.90). b- Border line ABI: (.9-.99). c- Normal ABI: (1-1.4). d- High ABI: (>1.4). 4) Coronary Calcification is measured using Agataston coronary calcium score (CCS), and patients are classified into 5 groups: a) CCS = zero. (Group A) b) CCS = 1-100. (Group B) c) CCS = 101-399. (Group C) d) CCS= 400-999. (Group D) e) CCS = 1000 or more. (Group E) ABI and clinical outcome There were statistically significant relation between Low and Border line ABI and presence of coronary calcification, while normal and high ABI are more associated with absence or low coronary calcification: - Highly statistically significant association between low ABI and presence of coronary calcification mainly in group C (p-value < 0.001), (odds ratio = 26) and group B (p-value < 0.05), (odd ratio = 6.86). - Highly statistically significant association between Border line ABI and presence of coronary calcification mainly in group C (p-value =0.01), (odds ratio = 7.7) . - No statistically significant association between High ABI and presence of coronary calcification. At multivariate analysis, this study indicated that low and border line ABI was independent risk factor predictive of high CCS, while high ABI was not. |