الفهرس | Only 14 pages are availabe for public view |
Abstract CHEMISTRY OF 4-0XO-THIAZOLIDINES 4-oxo-thiazolidines ( 2) are derivatives of thiazolidine (1) with a carbonyl group at position-4. -, --NH I . sJo (1) The substituents in the 4-oxo-thiazolidine ring in the 2,3 and 5-positions may be varied to give different derivatives, but the greatest difference in structure and properties is exerted by the group attached to the carbon atom in the 2- position, to give 2,4- dioxo-thiazolidine (3), 2-thioxo-4-oxothiazolidine (4), and 2-imino-4-oxo-thiazolidine (5), ring sys- -:.ems. O=C--NH S~C=O (3) SYNTHESIS OF 4-oxo-THIAZOL\DINES 1-from dithiocarbamates S=C---llNH (4) HN=C--NH S~C=O (5) Dithiocarbamates, formed by the reaction of ammon1. .a 1-3 pr1.. mary arru. nes 1-3 or arru. no ac1’.d s 4,5 w1. .t h car b on d1’ .su l p h1’ .de in the presence of a base, reacted with a-haloalkanoic acids to give the respective 2-thioxo-4-oxo-thiazolidines ( |