الفهرس | Only 14 pages are availabe for public view |
Abstract This study aimed to : Ovarian cancer is the second most common gynecological malignancy, more than 200,000 new cases diagnosed yearly worldwide. It represents the leading cause of gynecologic cancer-related death, The main reason for ovarian cancer poor prognosis is that about 75% of the cases are still diagnosed in advanced stage of disease, with limited prospect for cure, Patient prognosis depends on several patient and disease factors, following primary surgery were all associated with a better outcome, (Omura et al, 1991). Aim of the work: :(1) Study the value of pelvic and Para aortic lymphadenectomy and intra-abdominal complete debulking in patients with ovarian cancer on disease –free survival; complications and quality of life following the procedure. (2) Correlation of pelvic and Para aortic lymph nodes metastasis with stage of disease, differentiation of tumors, occurrence of distant spread, and survival of patients. Patients and methods: A randomized prospective study was done at Oncology Center, in which 77 patients with ovarian malignancies were classified into two groups .Group 1: In which 40 patients with ovarian malignancies were treated by radical hysterectomy + bilateral salpingoophrectomy, without lymphadenectomy, as a control group. Group 2 : in which 37 patients with ovarian malignancies were subjected to radical hysterectomy + bilateral salpingoophrectomy, + pelvic and Para aortic lymphadenectomy Results: Lymphadenectomy leads to longer disease free survival, over all survival without significant complications Discussion: these results cop with most other studiers. Conclusion: Lymphadenectomy leads to longer disease free survival, over all survival without significant complications. References: 152 references Summary: Addition of pelvic and paraaortic lymphadenectomy leads to increased disease free survival and overall survival |