الفهرس 
INTRODUCTION AND RATIONALEOnly 14 pages are availabe for public view
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Abstract
Measurement of common carotid artery intima-media thickness (CCA-IMT) with a B-mode ultrasonography is a valid approach for identifying and quantifying the presence of subclinical disorders. It is a noninvasive, sensitive, and reproducible technique for identifying and quantifying atherosclerotic risk. It is also a well-validated research tool that has been translated into clinical practice
Ultrasound measurement of carotid intima–media thickness (IMT) has become a valuable tool for detecting and monitoring progression of atherosclerosis and recently published recommendations provide guidance for proper standardization of these measurements. Important determinants of carotid IMT include age, gender, systolic blood pressure, diabetes mellitus and serum cholesterol levels.
Several studies suggest that intima–media thickness (IMT) and arterial elasticity indices may sensitively reflect different vasculopathic processes in children. However, normative values and the impact of adolescent growth are largely unknown.
It is common practice to call a CCA IMT >1.0mm as being abnormal, and >1.2mm as being high risk.
This study is a descriptive cross sectional study that had been conducted on healthy adolescent females in Ismailia city to measure carotid artery intema media thickness
Study included 119 healthy adolescent females aged 13-15 years who have normal weight and height for age, normal BMI for age and sex and normal blood pressure. with exclusion of those with Type 1 or type 2 Diabetes, who receive regular medications that can affect carotid
intima- media thickness (e.g. aspirin, cholesterol lowering drugs...etc) as well as persons with chronic illness (e.g. liver disease ,renal diseases …..) and Subjects who had carotid plaque on ultrasound.
Our study aimed at finding the normative value of carotid artery intema media thickness in healthy adolescent females aged 13-15 years in preparatory schools in Ismailia city.
One hundred and nineteen students were included in our study and all of them were subjected to history taking, weight and height measurement, blood pressure measurement and Ultrasound measurement of carotid intima–media thickness (IMT).
We found that Carotid IMT measurement at right side range from 0.20 to 0.84 ,while at left side range from 0.21 to 0.7 .with mean Carotid IMT= 0.45±0.1.
there is positive correlation between age and left carotid intema thickness (P Value >0.05 ) but not with right side
There is positive correlation between left carotid IMT and weight and height (P Value >0.05 ).
But negative correlation between carotid IMT on both sides and Systolic BP, Diastolic BP and Pulse Pressure.
Mean carotids’ IMT was slightly higher in right side than left side.
By the end of this work we were able to establish percentile of carotid intema media thickness for age in healthy adolescent females.
Measurement of common carotid artery intima-media thickness (CCA-IMT) with a B-mode ultrasonography is a valid approach for identifying and quantifying the presence of subclinical disorders. It is a noninvasive, sensitive, and reproducible technique for identifying and quantifying atherosclerotic risk. It is also a well-validated research tool that has been translated into clinical practice
Ultrasound measurement of carotid intima–media thickness (IMT) has become a valuable tool for detecting and monitoring progression of atherosclerosis and recently published recommendations provide guidance for proper standardization of these measurements. Important determinants of carotid IMT include age, gender, systolic blood pressure, diabetes mellitus and serum cholesterol levels.
Several studies suggest that intima–media thickness (IMT) and arterial elasticity indices may sensitively reflect different vasculopathic processes in children. However, normative values and the impact of adolescent growth are largely unknown.
It is common practice to call a CCA IMT >1.0mm as being abnormal, and >1.2mm as being high risk.
This study is a descriptive cross sectional study that had been conducted on healthy adolescent females in Ismailia city to measure carotid artery intema media thickness
Study included 119 healthy adolescent females aged 13-15 years who have normal weight and height for age, normal BMI for age and sex and normal blood pressure. with exclusion of those with Type 1 or type 2 Diabetes, who receive regular medications that can affect carotid
intima- media thickness (e.g. aspirin, cholesterol lowering drugs...etc) as well as persons with chronic illness (e.g. liver disease ,renal diseases …..) and Subjects who had carotid plaque on ultrasound.
Our study aimed at finding the normative value of carotid artery intema media thickness in healthy adolescent females aged 13-15 years in preparatory schools in Ismailia city.
One hundred and nineteen students were included in our study and all of them were subjected to history taking, weight and height measurement, blood pressure measurement and Ultrasound measurement of carotid intima–media thickness (IMT).
We found that Carotid IMT measurement at right side range from 0.20 to 0.84 ,while at left side range from 0.21 to 0.7 .with mean Carotid IMT= 0.45±0.1.
there is positive correlation between age and left carotid intema thickness (P Value >0.05 ) but not with right side
There is positive correlation between left carotid IMT and weight and height (P Value >0.05 ).
But negative correlation between carotid IMT on both sides and Systolic BP, Diastolic BP and Pulse Pressure.
Mean carotids’ IMT was slightly higher in right side than left side.
By the end of this work we were able to establish percentile of carotid intema media thickness for age in healthy adolescent females.