الفهرس 
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Abstract
The aim of this study was to investigate whether low level laser irradiation was able to improve ome biochemical parameters changes observed in the parotid and submandibularglands of iabetic rats and its effect on structures of those glands also studied. The glycemic state of the ats was also evaluated. Methods:Sixty adult female healthy wistar rats weight about 200-250 g were used.The rats were divided into four groups equal in numbers; The first group, (controlroup)represented the healthy untreated rats. The second group (diabetic group) received a ingle intraperitoneal injection with 50 mg/kg of streptozotocin (STZ). The third & fourth groups laser groups) also received the same dose of STZ as second group and subjected to low level aser irradiation with 5 & 20 J/cm² (Diode laser 870 nm ,100mW). After thirty days from nduction of diabetes the laser groups were exposed to the laser irradiation day after day for one week. The blood glucose level were measured before and after laser application.Then the rats were euthanized and the parotid & submandibular glands were removed for histological (light & lectron microscope)and enzymatic evaluation. Results: Rats in diabetic group showed lipid roplet accumulation in salivary glands but it decreased after laser irradiation. A decrease in asting glycemic level after laser irradiation was observed. Also, laser irradiation reduced the atalase and glutathione peroxidase activity in parotid and submandibular gland Conclusion: low level laser irradiation can affect enzymatic activity of salivary glands of trptozotocin induced diabetic rats.So laser irradiation may be used as an auxiliary therapy forcontrol of diabetic complications associated with salivary glands.