الفهرس | Only 14 pages are availabe for public view |
Abstract 1- Benzothiazoles are derivatives of thiazole, which belong to an important group of heterocyclic compounds. 2-Benothiazoles , which a cyanomethyl group at position 2 have been subject of extensive study in the recent past. 3- Numerous reports have appeared in the literature, which highlight their chemistry and use. 4- Diverse biological activities such as bactericidal, pesticidal, fungicidal, insecticidal, anti-inflammatory, and anti-thyroidal, have been found to be associated with thiazole and benzothiazole derivatives. 5- In recent years, several new methods for the preparation of 2- benzothizole derivatives and reactions have been reported in the literature. 6- 2-Cyanomethyl benzothizole, in the presence of various reagents, undergoes different types of reactions to yield other heterocyclic compounds, of biological and industrial interest. 7-These advance warrant to review the chemistry, biological properties of 2- cyanomethylbenzothiazole and to highlight its potential in evolving synthetic uses. |