الفهرس | Only 14 pages are availabe for public view |
Abstract Our study is a retrospective study of the files of the pathology at Ain Shams specialized hospital and Ain Shams university hospital in the 5 years (2001-2005) which was done to extract all cases of primary malignant tumors of the esophagus received during this period. Extraction of available clincophological data regarding age, sex, clinical presentation and the histological type was done with revision of available haematoxlin and eosin stained slides. The patients included in this study were 52 cases, the mean age was 50.8 ± 13.9 with range ( 22-72 ) years with higher incidence in age group from 50 to 70 years with male to female ratio 71.2:28.8 with seventeen (17) SCC cases the mean age was 58.6±11.9 with range (34.0-72.0%) with male to female ratio 76.5:23.5 while there were twenty two (22) EAC cases the mean age was 53.6±8.0 with range 38.0-72.0%. The clinical presentation of all studied cases was dysphagia, and epigastric pain with dysphagia was the main symptom in 78.8% of cases. All cases of SCC and EAC presented by dysphagia only while in cases of Barret’s esophagus the majority of cases presented by epigastric pain. Adenocarcinoma was the most frequent diagnosis (42.3%), followed by squamous cell carcinoma (SCC) (32.7%), while Barrett’s esophagus was the least frequent diagnosis (25%). More than half cases of SCC were grade II (52.9%), the remaining cases had equal frequencies (23.5%) of grades I and III. Half of cases of SCC were T3, followed by T2 then T1. Two thirds of cases were N 1(66.7%). More than half cases of EAC were grade II (54.5%), followed by grade III (27.3%), then grade I(18.2%).More than half of cases of EAC were T2(60%), followed by T3(40%). More than three quarters of cases were N1 (80%). |