الفهرس | Only 14 pages are availabe for public view |
Abstract 20 patients undergoing laser surgery of the inferior turbinate participated in the present study to compare the pre and post-operative changes of the symptoms and signs of allergic rhinitis, blood picture, IgE, interleukin-4, interleukin-5 and interferon-gamma. After one month of diode laser turbinoplasty, there was improvement in clinical symptoms like nasal obstruction, sneezing and rhinorrhea. Regarding the blood picture, there was marked relative eosinopenia while the total leucocytic count showed a significant increase. The erythroid series showed almost no changes. The operation was accompanied also with a significant decrease in IgE and interleukin-5, at the same time interleukin-4 and interferon-gamma showed insignificant decrease and increase respectively. These results denoted that diode laser inferior turbinoplasty improves not only the clinical manifestations of allergic rhinitis but it has also an immune effect by modulating T-cell function and tilting the Th1/Th2 balance towards Th1 dominant state. |