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Abstract Systemic lupus erythematosus is a chronic, autoimmune, inflammatory disease that can affect any organ system of the body. One of the commonest organs to be affected by organ-specific autoimmune injury is the thyroid gland. Both hypothyroidism and hyperthyroidism could be seen more frequent in SLE patients than in general population. Many studies discussed its prevalence. Hypothyroidism found to be the most common abnormality. These studies also found that thyroid autoantibodies found more frequently in SLE patients than general population. Aim of the present work was to assess thyroid dysfunction and thyroid auto-antibodies (Anti-TGA) in Egyptian juvenile SLE patients. This study was done on 20 SLE patients below 18 years old according to ACR criteria and 20 healthy controls. Informed consent obtained from the parents of all cases after full explanation of benefits and risks. |