الفهرس 
ChemistryOnly 14 pages are availabe for public view
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Abstract
Cancer and Alzheimer’s are two of the most prevalent diseases. Many trials were attempted to synthesize drugs targeting them adopting different rings as main core. So, by means of molecular modeling studies, structure activity relationship (SAR) and docking techniques, we managed to build new derivatives as anti-Alzheimer and anti-cancer and they were biologically screened for their activity. The adopted reactions afforded different new final compounds that were not mentioned in the available literature. Structure elucidation of the newly synthesized compounds was achieved through micro analytical analyses and spectroscopic methods. Molecular modeling studies were carried out using different softwares to predict the expected affinity of the newly synthesized compounds. Further pharmacological screening was done and the effect of the newly synthesized compounds.