الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
Carbimazole is an antithyroid drug belongs to the family
of thioamides. Carbimazole is a pro-drug as after absorption it is
converted to the active form, methimazole. Methimazole
prevents the thyroid peroxidase enzyme from coupling and
iodinating the tyrosine residues on thyroglobulin, hence
reducing the production of the thyroid hormones T3 and T4
(Thyroxin).
On the other hand, the use of carbimazole was
accompanied by side effects like headaches, pruritus (itching),
nausea, blood disorders, diarrhea, constipation, nausea, vomiting
and stomach aches, myalgia (muscle pain), arthralgia (joint
pain), jaundice (yellowing of the skin), hair loss, and a skin rash.
Other serious side effects may occur as bone marrow
suppression causing neutropenia and agranulocytosis. This may
occur at any stage during treatment and without warning and
accompanied by signs of an infection like a fever, a sore throat
or mouth ulcers.
In recent time, many natural products are being used to
protect the tissues from various drugs or chemicals-induced
toxicities. The rhizome of ginger (Zingiber officinale) is one
among of botanicals which play an important role in
pharmacology and treatment of various diseases. In traditional
Chinese and Indian medicine, ginger has been used to treat a
wide range of ailments including stomach aches, diarrhea.