الفهرس 
Introduction & Aim of the Work
Coronary Artery CalcificationOnly 14 pages are availabe for public view
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Abstract
The thesis aimed to evaluate safety and efficacy as well as long term outcomes after usage of RA in the setting of treatment of complex calcified coronary artery stenosis
We assessed the very long-term follow-up of a large cohort of unselected patients treated with coronary rotational RA. All 143 patients who underwent RA at LUMC from 2000 to 2013 and with complete baseline and follow-upinformation were analyzed in a retrospective manner.MACE were defined as the compositeof TVR, acute myocardial infarction, and all-cause mortality. The mean follow-up was 8.2 years.
The 10-year cumulative incidence of MACE for all patients was 57.9% (standard error [SE]: 5.0%). When comparing patients whoreceived a drug-eluting stent (DES; n = 68) versus patients who did not (balloon only, bare-metal stent, or none ofthe aforementioned; n = 75), the RA + DES demonstrated very long-term MACE of 49.2% (SE: 7.5%) versus 62.7% (SE: 6.1%),P = .160 with TVR as the most discriminating factor, 10.7% (SE: 4.0%) versus 29.2% (SE: 6.0%), P = .016.
Our results point toRA having reasonable long-term clinical results, especially in combined treatment with DES. To date, our study has the longest follow-up after RA.