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Abstract Abstract Background: Hypertension is a condition with a tremendous economic and public health impact which contributes to disability, health-care costs and mortality. It is the 1st leading global risk for mortality, as it is responsible for 13% of global deaths and 7% of disease burden in 2010. Hypertension may have a significant impact on the (HRQOL) of those who suffer from it. In Egypt, yet little is known about HRQOL and its associations with sociodemographic and clinical characteristics in patients with hypertension. Objective: To measure the HRQOL among hypertensive patients attending outpatient clinics at Ain Shams university hospital (Internal medicine hospital) and to determine the sociodemographic characteristics and clinical factors that may affect the QOL of those patients. Patients and methods: This study was conducted in the outpatient clinics in the Ain-Shams University hospital, as case-control study. A total of 300 subjects (150cases and 150 controls), of both genders and older than 18 years, were interviewed. Their socio-demographic and clinical data were collected by structured questionnaire; and HRQOL was assessed by using an Arabic version of two questionnaires - WHOQOL-BREF and COOP\WONCA scale. Results: Hypertensive patients reported lower scores in all domains of WHOQOL-BREF and COOP\WONCA scale when compared with normotensive. Multiple linear regressions revealed that male gender, employment, higher income, and increased number of used antihypertensive drugs were positively correlated with HRQOL. While, older age, BMI, longer duration of hypertension, increased number of doses, presence of symptoms and presence of co-morbidity were negatively correlated with HRQOL.COOP\WONCA scale and WHOQOL-BREF were significantly and negatively correlated with each other (P < 0.01). Conclusion: hypertension impairs the quality of life of patients who suffer from it. Keywords: Hypertension, health related quality of life, WHOQOL-BREF, COOP\WONCA scale. |