الفهرس | Only 14 pages are availabe for public view |
Abstract Acute limb ischemia (ALI) is one of the most common vascular emergencies. It is one of the most challenging and dangerous conditions in vascular surgical practice and carries a high risk of amputation and death when left untreated. Despite the progress in many areas of vascular reconstruction and endovascular techniques, acute peripheral arterial occlusion of the lower limb is still characterized by high rates of morbidity and mortality. Treatment is focused on rapid restoration of arterial flow to prevent major nerve and muscle infarction, while addressing underlying medical problems and comorbidities. Options in the management of acute arterial ischemia include anticoagulation with heparin, surgical revascularization, catheter-directed intra-arterial thrombolysis, and percutaneous mechanical and pharmacomechanical thrombectomy. A large number of randomized studies have been performed to try to answer the questions regarding how, when, and with what speed thrombolytic therapy should be started. |