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Abstract Conventional coronary angiography has been considered the gold standard method for diagnosis coronary lesions. However, coronary angiography is unlikely to be accepted in the absence of significant lesions and risk of complications due to its invasive features. Therefore, an alternative non-invasive procedure for detection of coronary artery disease (CAD) is necessary.Coronary CT angiography is unique in its ability to noninvasively visualize CAD and to accurately detect significantstenosis.Under certain prerequisites, which include a low and regular heart rate, a carefully performed coronary CT angiography investigation allows for the accurate detection of coronary artery stenoses. Especially, the negative predictive value has uniformly been found to be high, indicating that the technique may be most suitable as a non-invasive tool to rule out the presence of obstructive coronary lesions. The aim of this study is to evaluate the added value of CT coronary angiography for detecting coronary artery disease in mid and distal segment lesions using invasive coronary angiography as a reference standard. |