الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Obesity is a serious medical condition which is characterized by accumulation of excess fat in the body to the extent that it may have an adverse effect on health, leading to reduced life expectancy Bariatric surgery has become the only long-term effective treatment for severe obesity. Both of SADI-S and SG are considered now very popular single-stage procedures for the treatment of morbid obesity, with less postoperative complications. SADI-S has shown more rapid sustainable weight loss and comorbidity resolution when compared to these other procedures especially in the super-obese patient population. This procedure combines restriction, malabsorption, and hormonal changes to achieve weight loss and comorbidity resolution SADI-S has an advantage over SG as it is associated with the greatest weight loss and remission of diabetes. Ghrelin plays a significant role in regulating the distribution and rate of use of energy . Leptin plays a major role in the control of body fat stores through coordinated regulation of feeding behavior, metabolism, the autonomic nervous system, and body energy balance. BMI was significantly lower in SG group and SADI-S group 2 months and 4 months postoperatively .But, after 6 months, there was no significant difference between the two studied groups regarding body mass index . There was a significant difference between SG group and SADI-S group regarding serum ghrelin and leptin levels 6 months postoperatively. But, when comparing between the different times after surgery, there were high significant differences between the two studied groups regarding serum ghrelin and leptin. Conclusion: Both of SG and SADI-S are excellent solutions for treatment of morbid obesity. The short term results of SG is less positive than those obtained after SADI-S regarding reduction in body weight. There is a reduction in levels of ghrelin and leptin after SG and SADI-S but this reduction was more obvious with SADI-S than SG.