الفهرس 
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Abstract
Vital pulp therapy (direct pulp capping) aims to treat reversible pulpal injury whenever the pulp is exposed by caries, trauma, or restorative procedures. Preserving the pulp vitality, function and formation of reparative dentine are the ultimate goals of treatment. The Pulpal response is expressed by deposition of reparative dentine that seals the defect and compensates for the lost hard tissue,pulpal cells and provide protection against different stimuli. Materials and Methods: Eight non-specific race healthy dogs aged about 2-3 years, free of any systematic disease were selected for the study. The dogs were randomly assigned using www.randomizer.org into four groups according to the test durations (Early group,7 days and late group, 65 days). Four pulp capping materials were used in the current study. The capping materials employed were : a mineral trioxide aggregate, MTA ; a new tricalcium silicate-based cement, Biodentine ; nano-hydroxyapatite crystals ; and calcium hydroxide-based cement (Dycal). Results : Results demonstrated that MTA and Biodentine groups performed much better than other groups. Conclusion:Within the limitation of this study, we can conclude that direct pulp capping whenever indicated should be done as long as there is no contamination has happened. Tricalcium silicate-based cements and hydroxyapatite all showed much better results than CaH-based cement in terms of inflammatory response and tissue necrosis, formation of hard tissue bridge at the exposure site and can be considered as a suitable alternative to CaH-based cements.