الفهرس 
AcknowledgmentOnly 14 pages are availabe for public view
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Abstract
In this study fifty patients of ASA I and II aged between 20 and 50 years old of both gender were scheduled for elective laparoscopic cholecystectomy under general anesthesia in Gastroenterology Center at Mansoura University. Exclusion criteria were Patients who refuse to participate in the study, patients with uncontrolled diabetes, uncontrolled renal, hepatic or endocrine disease, coagulation disorders, allergy to any medication used in the study, body mass index >40 kg/m2, local skin infection and sepsis at site of the block or any psychiatric disorders.Patients were divided into two groups (twenty five patients in each group): group B : ultrasound guided transversus abdominis plane block with 18 mL of 0.5% bupivacaine + 2 mL saline in each side and group BD : ultrasound guided transversus abdominis plane block with 18 mL of 0.5% bupivacaine+ 2 mL dexamethasone (8mg) in each side. Visual analogue scale application was explained to all patients in the preoperative visit. Hemodynamic data as heart rate and mean arterial pressure of the patient were recorded before induction, after induction, after intubation and every 10 min intraoperatively till the end of surgery and at 30 min, 1h, 2h, 6h,12h and 24h postoperatively. Visual analogue score were recorded at 30 min ,1h, 2h, 6h, 12h and 24h postoperatively. Also, time of first analgesic requirement , total morphine consumption and any postoperative nausea and vomiting occuring in 1st 24 h were recorded. The results proved that adding of dexamethasone to bupivacaine for ultrasound guided transversus abdominis plane block made the analgesic duration longer, postoperative pain amd morphine consumption has been decreased and with less incidence of nausea and vomiting after laparoscopic cholecystectomy