الفهرس | Only 14 pages are availabe for public view |
Abstract Objectives: To quantify the incidence of major adverse events occurring in hospital or as late outcome of coronary artery bypass graft surgery, and to identify the risk factors for these adverse events. Methods: This study is conducted on patients who undergone isolated CABG surgery at the Cardiothoracic Academy Hospital throughout the whole 2014, 2015, and the first 4 months of 2016; Data was collected retrospectively from 607 patients to report postoperative incidence of major adverse cardiac events in hospital and up to two years after surgery. In addition to in hospital mortality, the endpoints were the composite occurrence of late adverse events; including all-causes of mortality or re-hospitalization for a cardiovascular-related illness included: heart failure, reinfarction, recurrence of angina pectoris and repeat PCI or CABG, cerebrovascular stroke and death. Incidence of these events was calculated overall, and odds ratios of selected adverse events were computed according to risk factors. Results: 607 patients met all inclusion criteria. The average incidence in hospital mortality was (7.1%.) The incidence of late adverse events was: hospital readmission due to cardiac cause (7.6%), CCU admission (6.8%), angina pectoris or myocardial infarction (5.1%), coronary angiography (3.3%), coronary angioplasty (1%), redo CABG (0.2%), heart failure (3.8%), cerebrovascular stroke (0.7%), death (2.1%). This study showed that age, female gender, diabetes mellitus, history of cerebrovascular events, hyperlipidemia, prolonged cross clamp and bypass times, and coronary endarterectomy are all associated with increased mortality after CABG. Conclusion: This study shows that the incidence of in-hospital mortality and major adverse events post CABG varies highly depending on many factors that can be categorized into groups: patient’s group characteristics, intraoperative factors, and postoperative factors. Fortunately, these factors are modifiable and should be identified and monitored early. |