الفهرس 
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Abstract
Our study was planned to study the effect of Pediococcus on the: Hematological parameters of treated calves as (hemoglobin, erythrocytes counts and leukocytes counts, differential leukocytes count, PCV, MCV, MCH, MCHC, thrombocytes count). On biochemical parameters of treated calves as (total protein, albumin, globulin, ALT, AST, alkaline phosphatase, calcium, phosphorus, sodium, potassium, urea, creatinine, metabolic hormones (T3 and T4) and Protein electrophoresis). On body weight and body gain of treated calves. Reproductive performance of female (first cycle, number of insemination, number of repeat breeder (service/breeder) and pregnancy diagnosis. Our study was performed on twenty Holstein calves (10 male and 10 female), 40-60 days old and 53-89 kg B.wt at Damietta governorate in special dairy farm were divided into four groups (5 male and 5 females as a control group) and (5 male and 5 female under our experiment); all groups under the same hygiene management and the same nutrition (starter ration 21% - Al-Asema group Company + milk before weaning while after weaning the ration were be 18% until reach 200-220 kg B.wt then 16% ration till reach moreover 350 kg B.wt. from the same company). Every calves under our experiment (10 calves) were take 10 gm. Maxboost* after fermentation in 100 ml water for 2 -3 hours then added to the milk one time per day for one month, then after 1 month give the drug for 3 successive days 20gm/head/once daily in drinking water after fermentation for 2-3 hours for five months. Body weight were determined in the beginning of the experiment and every week for 4 weeks then every 2 months for 10 months to the all groups. from this study it was concluded that the use of Pediococcus (23×106 CFU/calf/day) orally in drinking milk once daily for one month have highly significant effect on blood picture ,liver function tests, kidney function test, metabolic hormones protein electrophoresis and body weight in calves.