الفهرس 
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Abstract
Glomerulonephritis (GN) is responsible for 16% of all causes of end-stage kidney disease. Although much is known about the clinical characteristics and natural history of the glomerulopathies, very little information on the epidemiology of these diseases is available from reviews. Insight into the baseline incidence of glomerulonephritis (GN) throughout the world can provide important information on trends of disease occurrence by sex, age and geographical location.
In order to outline the prevalence of different glomerular diseases among patients presenting to menoufia university hospitals, a total of 136 renal biopsies, were analyzed according to the reported clinical indications for biopsy.
The mean age of the studied patients was 35.9 ± 14. 6, 50.7%) of the studied patients were males and 67 (49.3 %) were females &25 (18.38%) of the studied patients were smokers and 111 (81.62%) were non-smokers.
The outstanding feature was the high prevalence of FSGS.
LN was the second most commonly encountered disease in the whole group. It has the best prognosis, 76% of the patients presented with class IV lupus nephritis
Membranous nephropathy was reported in (13.23%),
Membranous nephropathy prognosis depends on presentation of disease Risk stratification.
Vasculitis was reported in (12.5%), this reflects the general trend of increased incidence of vasculitis world-wide.
Other pathological findings were minimal change disease (5.9%), membranoproliferative GN (3.7%), amyloidosis (5.9 %),
Summary
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infection related GN (2.9%), TMA (4.4%), global glomeruloscelerosis (3.7%), other non-glomerular (interstatial or tubular injury) (7.3%).
As regard response to treatment across the whole studied patients regardless the pathological finding and treatment 23% show no response to treatment and continue as CKD OR ESRD according to the presentation, 37% show partial response in the form of decrease in proteinuria or improvement of kidney function but not reaching the target while 40% of the patients show complete response..
16% of our patients presented with hematuria, the pathological pattern of GN in patients presented with hematuria, vasculitis was reported in 17 (77.27%) cases. infection related GN (13.7%), membranoproliferative (4.5 %) and Lupus nephritis (4.5%).
The histopathological lesions in patients with low GFR, FSGS was reported in (21%),vasculitis (27%), Lupus nephritis (8%), Membranous nephropathy (9.5%), amyloidosis (6.5 %), infection related GN (6.5%), TMA (8%), global glomeruloscelerosis (8%), minimal change disease (1.5%), membranoproliferative GN (3 %).
The histopathological lesions in patients with nephrotic range proteinuria, Lupus nephritis was reported in (19.5%), FSGS (24%), membranous (15 %), vasculitis (11%), TMA (4.5%), minimal change (7), membranoproliferative GN (4.5%), amyloidosis (6.25%), infection related GN (3%).
The histopathological lesions in patients with non nephrotic range proteinuria, Cryoglobulinemic vasculitis (36%), lupus nephritis was reported in (21 %), FSGS (21%), membranous (7 %), TMA (7%), infection related GN (7%).
FSGS is the common type of GN in males, While Lupus nephritis is the most common in females.