الفهرس 
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Abstract
Radiation therapy is a safe and effective modality for the treatment of cancer. External Beam Radiation therapy is an important therapeutic option for men diagnosed with clinically localized and locally advanced high-risk prostate cancer. The primary goal of 3DCRT and IMRT, is to complete destruction of an entire tumor cells and sparing the critical surrounded organs.
Integral dose is the volume integral of the dose deposited in a patient and is equal to the mean dose times the volume irradiated to any dose. ID is relatively independent of treatment planning parameters. The majority of ID was deposited in normal tissue.
This study includes twenty five male patients with prostate cancer. For every patient two different EBRT technique carried out. The 3DCRT and IMRT plans are evaluated for each patient to obtain one most optimum plan for each and obtain validity to treatment according to full dose delivery to target and sparing organ at risks by implementing does parameters. These techniques were designed using TPS, at Alexandria Ayadi Al-Mostakbal Oncology Center (AAAOC).
The results of the current study showed that, for the treatment target (PTV) of prostate cancer in case of 3DCRT and IMRT. The all mean values of PTV parameters of IMRT are better than 3DCRT. The parameters of target covering plan acceptance 98%, 95%, 92%, 50%, 5%, 2%, and show that significant differences except HI is not statistically significant. The monitor unit for IMRT is higher than 3DCRT.
The best plan should achieve better and homogeneous dose distribution to the PTV. The minimum and maximum acceptable radiation doses to the PTV should be (95% - 107%) which is achieved by the IMRT. Thus, we can demonstrate that the dose coverage to the PTV was better in IMRT plan than 3DCRT plan.
For Organs at Risk and NTT, with respect to ID parameter for organs at risk, the comparison of 3DCRT plan with IMRT plan showed that, the integral doses of Bladder, Penile Bulb, NTT, and, NTT (2%, 5%, 10%, and 15%) irradiated with 3DCRT were better than that for IMRT plan. and those doses were within the dose tolerance of the prostate Cancer Organs at Risk.