الفهرس 
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Abstract
Introduction : The presence and the development of esophageal varices (EV) is a clinical manifestation of PH with a prevalence that can range from 40% to 80% in patients with cirrhosis. Endoscopic screening for EV and gastric varices should always be performed when a diagnosis of cirrhosis is made. There is a potential usefulness of IR as simple, noninvasive, and easy-to-get test for predicting EV in patients with Child A cirrhosis caused by hepatitis C virus (HCV) • Aim of the work : Evaluation of the validity of insulin resistance in prediction of esophageal varices in patients with compensated hepatitis C virus induced cirrhosis. • Patient and methods : This study included 70 non-diabetic, non-obese patients with Child class A HCV induced cirrhosis. Advanced cirrhosis and hepatocellular carcinomas and other causes of liver disease except HCV are excluded .upper endoscopy and abdominal and pelvis US are done . HOMA-IR calculated. • Results : The HOMA-IR score gave the highest accuracy at a cut-off value of 3.45 with (sensitivity 95.8 % and specificity 86.4%). The next highest accuracy was right liver lobe diameter /albumin ratio at a cut-off value of 3.67 with (sensitivity 89.6% and specificity 72.7%).The least accurate was the platelet count/spleen diameter ratio at a cut-off value of 677.7. • Conclusion : we can conclude that HOMA-IR score can offer valuable information regarding the diagnosis and grades of oesophageal varices.