الفهرس | Only 14 pages are availabe for public view |
Abstract The present study was set up to assess the prevalence of different traumatic vertebral column and spinal cord disorders in dogs and cats with diagnosis, trials of interference and follow up of these disorders through a clinical work (clinical study) and to evaluate the role of PRP, BM-MSCs and their combination in treatment of acute compressive spinal cord injury in a rat model (experimental study). Fifty six clinical cases were diagnosed with traumatic vertebral column and spinal cord disorders in dogs and cats and evaluated using neurological examination, plain radiographs, melography, CT and MRI with postmortem and histopathologiacal examination of the euthanized cases. Different trials of interference according to each affected in addition to follow up were adopted. Spinal trauma was the main cause of vertebral column and spinal cord disorders which occurred in different ways like, motor vehicle accidents (26.8%), falls (35.7%), stepping by someone or other animal (14.3%) and direct trauma with hard object (23.2%). Motor vehicle accident was the most common cause in dogs (45 %) while falls was the most common cause of spinal trauma in cats (44.4%). The affected cases were classified according to the lesion localization in the affected cord segments as C1-C5 (13%), C6-T2. |