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العنوان
Lipid and Hormonal Profile in Male Androgenic Alopecia /
المؤلف
Shoaib, Reham Ragab.
هيئة الاعداد
باحث / ريهام رجب شعيب
مشرف / فاطمة يوسف صالح
مشرف / محمود حمدي أحمد
الموضوع
Dermatology.
تاريخ النشر
2021.
عدد الصفحات
87 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنيا - كلية الطب - الأمراض الجلدية والتناسلية
الفهرس
Only 14 pages are availabe for public view

from 97

from 97

Abstract

Androgenic alopecia is a patterned scalp hair loss caused mainly by systemic androgen and genetic factors. Many Studies showed an association between androgenic alopecia and metabolic syndrome or its associated diseases including cardiovascular diseases, hypertension and insulin resistance .
The present study was conducted on males with androgenic alopecia aged between 20- 55 years. Diagnosis of androgenic alopecia depend on history and clinical findings including early age of onset (<35 years) and pattern of increased hair thinning on frontal and parietal scalp with greater hair density on the occipital scalp. BMI was measured, Hormonal and lipid profile were done for these patients.
Our results revealed :
1)Distibution of male androgenic alopecia according to age was <30 years (20%), ≥30-40 years (53.3%), >40 years (26.7%).
2)According to BMI the percentage of normal weight AGA patients were (13.3%), overweight patients were (66.7%) and obese patients were (20%) .
3)As regard the hormonal profile in our study
• DHEA-S, Testosterone, LH and FSH levels showed no statistically significant difference between abnormal and normal level patients.
4)As regard hormonal profile in different age groups, patients<30 years have the highest DHEA-S level. Patients ≥30-40 years have the highest total testosterone level and the lowest LH and FSH levels. Patients>40 years have the highest LH and FSH levels.
5)As regard relation between BMI and hormonal profile, normal weight patients have the highest LH and FSH levels and the lowest DHEA-S and total testosterone levels. Obese patients have the highest DHEA-S and total testosterone levels and the lowest LH and FSH levels.
6)As regard lipid profile, there was statistically significant difference between number of patients with abnormal and normal LDL, HDL, triglycerides, and cholesterol levels.
7)As regard lipid profile in different age groups, patients<30 years have the highest HDL level and the lowest LDL, triglycerides and cholesterol levels. Patients>40 years have the highest LDL, triglycerides and cholesterol levels.
8)As regard relation between BMI and lipid profile, normal weight patients have the highest HDL levels and the lowest LDL, Triglycerides and cholesterol levels. Obese patients have the highest DHEA-S, total testosterone, LDL, Triglycerides and Cholesterol levels and the lowest HDL levels.
In conclusion,
In AGA patients, not significant relation is present between AGA and hormonal profile of patients. Also, a significant relation is present between lipid profile on one hand and AGA on the otherhand which is one of the components of metabolic syndrome.
Recommendations
We recommend that AGA patients should be investigated for lipid profile. Age and BMI should be put in mind in these cases for risk of associated cardiovascular diseases.
We recommend further studies to clarify the following topics:
1. The association of AGA and other components of metabolic syndrome as insulin resistance and hypertension.
2. The association of AGA with other components of metabolic syndrome in one hand and age on the other hand.
3. The association of AGA with other components of metabolic syndrome in one hand and BMI on the other hand.
4. Study effect of controlling body weight in patients with androgenic alopecia.