الفهرس | Only 14 pages are availabe for public view |
Abstract This study evaluates the clinical and microbiological effects of Bifidobacterium probiotic gel as an adjunctive therapy to scaling and root planning (SRP) in chronic periodontitis patients. Patients and Methods: Thirty moderate chronic periodontitis patients (18 females, 12 males, aged between 30 and 50 years) were involved in the study. They were classified into 3 groups randomly. 1st group composed of 10 patients who received SRP associated with the subgingival application of Bifidobacterium probiotic gel, 2nd group composed of 10 patients who received SRP associated with the subgingival application of Chlorhexidine gel and 3rd group composed of 10 patients who received SRP only. Local drug delivery was applied once weekly for six weeks. All patients were evaluated clinically by measuring (Plaque Index (PI), Gingival Index (GI), Pocket Probing Depth (PPD) & Clinical Attachment Level(CAL)), and microbiologically by culturing subgingival plaque samples anaerobically for detection of total bacterial count, p.intermedia & p.gingivalis counts at baseline and after six weeks of periodontal treatment. Results: All periodontal parameters (PI, GI, PPD and CAL), total bacterial count in addition to p.intermedia & p.gingivalis counts revealed a statistically significant difference after six weeks of treatment among all the groups. However, by comparing post-treatment values of p.intermedia & p.gingivalis counts in between groups demonstrated a statistically significant difference between groups 1&3 also between groups 2& 3. Conclusions: The local application of Bifidobacterium probiotic gel offers a promising therapeutic approach in periodontal treatment as adjunct to SRP. |