الفهرس 
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Abstract
This study was conducted during the period from August 2017 to December 2020 as a prospective clinical trial in Assiut University Hospitals. The study was approved by the Scientific Ethics Committee of Faculty of Medicine of Assiut University, and informed written consent was obtained from the patients to deal with their data for scientific purposes. The objective of the study was to evaluate the efficacy and safety of multivessel minimally invasive coronary artery bypass graft surgery and to evaluation of intraoperative complications and assess outcomes. During our study period, we included 67 patients who met the inclusion criteria of this study. They were divided into 2 main group: MICS CABG (minimally invasive multivessel coronary artery bypass) and OPCABG (conventional Off pump coronary artery bypass surgery) We found that the mean time in minutes needed for MICS CABG group was significantly more than time needed in OPCABG group , we also found that the bleeding amount and the amount of the transfused blood was significantly less in the MICS CABG group when compared to OPCABG group, We did not find any statistically significant differences between both group as regard to the occurrence of arrythmia, Cardiac arrest, need for IABP and CPB and the mortality outcome Regarding to the postoperative results, we found that the mean duration of hospital stays was significantly less in MICS CABG group (6.21± 1.80) when compared to OPCABG group (10.71 ± 1.93). Also, we found that patients in MICS CABG group regained their normal activity in a period less than needed by OPCABG group (9.67 ± 1.67) and (50.79 ± 8.77) respectively, with a highly significant P-value<0.001. Taking in consideration that both groups were subjected to the same type of anesthesia, we found that in the 2nd day postoperative all patients in MICS CABG group reported mild to moderate pain, however the majority of patients (94%) in OPCABG group reported sever to worst pain possible with highly significant P-value<0.001. On the other hand, in the 5th day post-operative the degree of pain in MICS CABG group ranged from no to mild pain, however all patients in OPCABG group had a moderate degree of pain with significant P-value<0.001.