الفهرس | Only 14 pages are availabe for public view |
Abstract Aim: The aim of this study is to assess the effect of an experimental gluten free toothpaste on the ulcerative events in children with celiac disease. Thus, providing the celiac children with gluten,sodium lauryl sulphate (SLS), fluoride, and paraben free toothpaste without inducing inflammatory or immune reaction. Such toothpaste is not available in the Egyptian market. A gluten free toothpaste was formulated and produced for this study. Methodology: Twenty children diagnosed with celiac disease, aged from 6 to 15 years and on strict gluten free diet were recruited from gastroenterology clinic at New Children University Hospital (Abo El Rish Hospital). Each participant was provided with a tooth brush and an experimental toothpaste. The parents were asked to use the gluten free toothpaste 3 times daily for their children and report every time if there is any inflammation or any reaction associated with using the toothpaste. All children were recalled weekly for follow up during the first month and at 3 & 6 months after using the toothpaste for assessment. Results: During different follow-up intervals (starting from one week until 6 months), all the cases were free from any ulcers and/or inflammation with 100% success rate during toothpaste use. Conclusion: The toothpaste did not cause any undesirable side effect during use. Almost all children were satisfied with the toothpaste. |