الفهرس | Only 14 pages are availabe for public view |
Abstract Nature is an ancient pharmacy that used to be the solitary source of therapeutics for the early eras. The marine habitat is a prolific source of bioactive secondary metabolites with the potential to treat several diseases. Besides the chemical novelty associated with these compounds, some of them possess novel mechanisms of action as well. The recently approved marine drugs represent noteworthy examples. The largely unexplored marine world that presumably harbors the most biodiversity may be the vastest resource to discover novel ‗validated‘ structures with novel modes of action that cover biologically relevant chemical space. Several challenges, including the supply problem and target identification need to be met for successful drug development of these oftentimes complex structures. The high degree of innovation in the field of marine natural products will lead to successful marine drug discovery and development. The progress in marine drugs natural products will form a new wave of drugs that flow into the market and pharmacies in the future. |