الفهرس | Only 14 pages are availabe for public view |
Abstract Chronic kidney disease (CKD) is a major public health problem worldwide and is associated with a considerable increase in morbidity and mortality, cardiovascular disease is most common cause of death among chronic kidney disease patients. There is an increasing interest in using vitamin D levels as a novel marker for CVD, because epidemiological data have shown a strong correlation between the risk of CVD and vitamin D deficiency. The aim of study was to determine the association between serum vitamin D level and cardiac functions assessed by tissue Doppler imaging in chronic kidney disease patients. Patients and methods: our study conducted on 90 patients from outpatient clinic or inpatient department of national institute of nephrology and urology. All patients were subjected to full history , full clinical examination, laboratory investigations including : serum urea , serum albumin , complete blood picture, serum electrolytes (calcium and phosphorus), PTH, serum vitamin D , lipid profile and echocardiography and Tissue Doppler imaging . Conclusion: serum vitamin D is positively correlated with diastolic function among CKD patients, increased incidence of left ventricular hypertrophy in CKD patients especially with vitamin D deficiency ,Tissue Doppler imaging is more accurate than echocardiography to estimate diastolic function. |