الفهرس 
Normal skin anatomyOnly 14 pages are availabe for public view
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Abstract
Background: The main stay for treatment of major burns is early excision and coverage. Nevertheless, the skin autografts is the gold standard for coverage but in major burns, the donor for autografts is limited. So, normal skin substitutes are considered as an advantageous alternative. Although they are limited due to their cost and availability. Skin allografts are a rich source which was considered as a medical waste and thanks to bariatric surgery which assisted obese patients to lose weight leaving them in a need for different body contouring procedure.
So, this study aimed to evaluate the pathological and clinical effects of skin Allografts from Massive Weight Loss donors to treat major burn.
Patients and Methods: A total of 80 patients with major burns underwent early excision in (early 48 hrs. post trauma) and covered by either: Allografts from MWL donors (in group I) or by: non MWL Allografts (group II). Biopsies were taken and examined for the effect of allografts over the wound bed and the Photographic Wound Assessment Tool (PWAT) was applied to evaluate the percentage of improvement after applying different types of skin substitutes
Results: Percentage of improvement was significantly higher among patients who used Allografts from non-massive weight loss donors when compared with patients who used Allografts from massive weight loss donors.
Conclusion: Non MWL allografts are of better results in the take of the 1st dressing change and in the detachment day. Moreover, patients who received Allografts from MWL developed sepsis that increased their hospital stay and hence more complications. Yet, MWL donors are a reliable source for allografts until cadaveric skin donation is legalized especially in major burns treatment as the donor is not always sufficient for coverage so, the use of skin Allografts is a life-saving alternative.