الفهرس | Only 14 pages are availabe for public view |
Abstract The present study was established to estimate cephradine residues in broiler chicks using HPTLC and to determine the efficacy of potassium citrate in reducing these residues. A total number of 40 Hubbard chicks of 21 days old were used in this study after dividing into 2 equal groups (each of 20 chicks) when reached 30 days old. Cephradine (Atocef forte®) was given as oral dose of 0.5 gm/liter twice daily for five consecutive days to group (1 ) and was given twice daily for first 3 days but at last 2 days, cephradine was given for 12hr, potassium citrate for another 12hr to group (2). Cephradine concentrations were assayed in serum, liver, kidney and breast muscle of broiler chicks at 24, 48, 72, 96hr post last dose. It could be concluded that, cephradine can be detected in kidney, liver at highest concentration with the lowest concentration in serum and breast muscle. Oral administration of potassium citrate result in disappearance of residues from breast muscle and liver 1 and 2 days earlier than when cephradine was administered alone where in kidney, cephradine residues were still measurable up to 4th day at very low concentration. |