الفهرس | Only 14 pages are availabe for public view |
Abstract Pseudomonas aeruginosa is a Gram-negative bacterium that can cause diseases in humans, animals and plants. These diseases are difficult to treat due to the natural resistance of these bacteria. It also has the ability to obtain more resistance mechanisms for several groups of antimicrobial agents. Antibiotics including (beta-lactams, quinolones, aminoglycosides and polymyxins), medicinal plants including (Eucalyptus citriodora, Eucalyptus rostrata, Myrtus communis and Callistemon lanceolatus) are broad-spectrum antibacterial agents used in treat these diseases. Among all plant ethanolic extracts, Eucalyptus rostrata was the most active one followed by Eucalyptus citriodora, the activities of medical herbal plants extracts against P. aeruginosa isolates used have shown good activity as compared with the recommended antibiotics. By using real-time PCR, the expression of efflux pump genes (mexY and mexB) of P. aeruginosa bacteria was high compared with the expression after treatment with plant extract (Eucalyptus rostrata). By using GC/MS for the most potent plant (Eucalyptus rostrata), Spathulenol had the highest amount in its essential oil followed by cryptone. |