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العنوان
CANCER CHEMOPREVENTION BY METFORMIN
HYDROCHLORIDE COMPARED TO PLACEBO IN ORAL POTENTIALLY MALIGNANT LESIONS:
المؤلف
AbdelAzim,Ahmed Adel Mohamed
هيئة الاعداد
باحث / احمد عادل محمد عبدالغظيم
مشرف / فتحيه زهران
مشرف / جيهان غريب مدكور
مشرف / هبه احمد فراج
الموضوع
Metformin, oral potentially malignant disorders, premalignant, cyclin D1, miRNA-21, dysplasia, oral cancer, cancer chemoprevention, oral squamous cell carcinoma. oral potentially malignant disorders oral cancer oral squamous cell carcinom
تاريخ النشر
2021
عدد الصفحات
203p,leaves:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Periodontics
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة القاهرة - الفم والأسنان - oral Medicine
الفهرس
Only 14 pages are availabe for public view

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from 229

Abstract

The aim of this study was to compare the effect of metformin hydrochloride on oral potentially
malignant disorders (OPMDs) to placebo regarding its efficacy in regression or suppression of the
progress into frank cancer.
Hypothesis: We hypothesized that metformin can exert an antineoplastic effect and suppress
the progression of oral potentially malignant lesions into frank cancer