الفهرس | Only 14 pages are availabe for public view |
Abstract Clinical research shows that pomegranates, when part of a healthy diet, might help prevent heart disease, heart attacks and strokes. This is because pomegranates have the potential to thin the blood, increase blood flow to the heart, reduce blood pressure, reduce plaque in the arteries, and reduce bad cholesterol while increasing good cholesterol. Pomegranate extracts have been shown to scavenge free radicals and decrease macrophage oxidative stress and lipid peroxidation in animals and increase plasma antioxidant capacity in elderly humans. This study was conducted to investigate the effect of supplementation with dry pomegranate (Punica granatum) powder on biomarkers of lipid oxidation and antioxidants status in mild cardio vascular disease patients. Sixty adult men suffering from mild CVD (stage 1) were selected randomly from outpatient clinic of cardiopulmonary department in El- Fayoum governorate, their ages more than 45 years. They were diagnosed by the physician as mild CVD (stage 1). Patients with bronchial asthma, diabetes mellitus and mental health problems such as depression and anxiety are excluded from the study. The patients were divided randomly into two equal groups (A&B): group A (Control group); consisted of thirty patients. They received (starch powder) for 8 weeks. group B (Study group); consisted of thirty patients. They were supplemented with 50gm of dry pomegranate powder, one time per day for 8 weeks Nutritional Assessment (Mean daily nutrient intake using 24 Hours recall and Dietary history), Anthropometric measurements (Body mass index, Waist Hip Ratio and Arm Circumference), Blood pressure and Heart Rate were assessed, blood analysis for TC, TG, LDL and HDL and Antioxidants analysis (MDA, SOD, GSH, CAT and VIT C) for both groups A and B before and after supplementation. Results showed that; in group A, there was no significant difference in the mean value of WHR, AC, systolic blood pressure, diastolic blood pressure, cholesterol, triglyceride, LDL, HDL, MDA, SOD, GSH, CAT and VIT C post supplementation in comparison with pre supplementation values and in group B there was significant difference in the mean value of systolic blood pressure, diastolic blood pressure, cholesterol, MDA, SOD, CAT and VIT C post supplementation in comparison with pre supplementation values, While there was no significant difference in the mean value of Arm Circumference, WHR, triglyceride, LDL, HDL and GSH post supplementation in comparison with pre supplementation values. |