الفهرس | Only 14 pages are availabe for public view |
Abstract In children, prevention of initial dental caries has an essential role instead of treatment. The non-invasive care of non-cavitated carious lesions utilizing remineralization techniques to heal the enamel has earned more interest from the scientific community in recent years. Aim : To evaluate the remineralization potential of Self assembling peptide (P11-4), Nano-Hydroxyapatite (Nano-HA) and Casein Phosphopeptide-Amorphous Calcium Phosphate and Fluoride (CPP-ACPF) using Energy dispersive X-ray Analysis and Scanning Electron Microscopy (EDX /SEM). Material and Methods : Forty enamel specimens of primary second molar were prepared, then placed in a demineralizing solution with a pH of 4.4 for 96 hours at 37°C to induce artificial carious lesions. Specimens were divided randomly according to the remineralizing agents into four equal groups: group A : control group (artificial saliva), group B : Self-assembling peptide (Curodont repair), group C : Nanohydroxyapatite paste and group D:CPP-ACPF (GC MI Paste Plus). Remineralization was carried out for a period of 21 days. Calcium and Phosphorous content was evaluated using EDX and SEM for all specimens. The data were collected and analyzed statistically using One-Way-ANOVA test. Results : After remineralization, the Calcium/Phosphorous ratio (Ca/P) was significantly higher using Self-assembling peptide and Nano-HA. However, the increase in CPP-ACPF was non-significant compared to control group using EDX. On SEM examination, there was a restoration of enamel surface with appearance of mineralized deposits. It was highly observed in group B and group C then group D and the lowest was in group A. Conclusions : Self-assembling peptide and Nano-hydroxyapatite found to be more effective compared to CPP-ACPF in remineralization. |