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Abstract Aim: This study was conducted to evaluate the accuracy of linear measurements performed on mandibular anaesthetic landmarks obtained by ultra-low-dose cone beam computed tomography and digital panoramic radiography in comparison with real measurement on dry mandible. Methodology: A total number of nine dry human mandibles were selected and mandibular anaesthetic landmarks were marked using gutta-percha. The dry mandibles were submitted for digital panoramic radiography and cone beam computed tomography with mini-dose parameters using the SOREDEX CRANEX{u2122} 3Dx unit, linear measurements were performed on SCANORA Lite image viewer and OnDemand 3D viewer. The real linear measurements were measured using digital caliper. Results: There was a statistically significant difference in all measurements performed on digital panoramic radiographs, reformatted panoramic images underestimate real linear vertical measurements without significant difference, the absolute error for the cross-sectional views of CBCT ranged from 0.0001 to 1.44mm for mandibular foramen linear measurements, using mini-dose parameters did not affect image quality nor measurements accuracy. Conclusions: Linear measurements driven from CBCT cross-sectional images using On Demand software are accurate and have the lowest error value; therefore it is considered one of the most important imaging modality for preoperative surgical site assessment |