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Abstract Background: chronic pelvic pain (CPP) is a common gynecologic problem that has a substantial negative effect on women, their lives and their communities. Objectives: To determine the effect of neurogenic acupoint dry cupping therapy on degree of inflammation, pain perception & intensity, and life impact of pelvic pain in women with chronic pelvic pain, with regarding to the biological and neurophysiological impacts of dry cupping on acupoint. Subjects: Thirty women with CPP were randomly divided into two equal groups; the study group receiveddry cupping on neurogenic acupoints plus lifestyle modifications for 8 weeks(n=15), while the control group received only lifestyle modifications for 8 weeks(n=15). Methods: Women were assessed pre- and post-treatment with thehigh sensitive C-reactive protein (hs-CRP) levels, the short-form McGill Pain Questionnaire (SF-MPQ), and the pelvic pain impact questionnaire (PPIQ).Results: Comparing both groups post-treatment revealed that there were significant reductions in levels of hs-CRP, and scores of SF-MPQ &PPIQ (p < 0.05) in favour of the study group. Also, there were significant positive correlations between hs-CRP and both SF-MPQ (PRI, VAS & PPI) & PPIQ (p < 0.05).Conclusion: Neurogenic acupoint cupping had significantly improving effects on the degree of inflammation, pain perception & intensity, and life impact of pelvic pain in women with CPP |