الفهرس | Only 14 pages are availabe for public view |
Abstract In this study, the antibacterial activity of camel milk, camel serum, camel milk purified protein, and camel serum purified protein was tested against Staph aureus and E. coli. camel serum and camel milk have marked antibacterial effect against E. coli and Staph aureus while camel milk purified protein and camel serum purified protein showed no inhibitory activity, the antifungal activity was tested against Candida albicans and Aspergillus fumigatus. Camel serum, camel milk and their purified proteins showed no inhibitory activity against both microorganisms. By detection of some pro-inflammatory biomarkers and immunological parameters in camels’ sera of apparently healthy camels and diseased camels suffered from respiratory manifestation, there was a marked increase in the levels of IL-1, IL-6 and TNF-α in diseased camels than healthy ones but there was a decrease in IL-10 in diseased camels than the healthy ones. There was a marked elevation in the levels of acute phase proteins (fibrinogen, Abstractceruloplasmin, haptoglobin, and serum amyloid A) in diseased camels compared to healthy ones. The level of NO and MDA was elevated in diseased camels while the level of catalase and Glutathione reductase enzymes was decreased in diseased camels compared to healthy ones. Serum levels of C3 and C4 decreased significantly in diseased animals compared to apparently healthy ones while there was a marked increase in the serum levels of IgA, IgM and IgG in the diseased animals compared to healthy ones. There was a marked increase in the levels of total protein, alpha 1globulins, alpha 2 globulins, beta 1 globulins, beta 2 globulins, gamma globulins and total globulins in diseased camels compared to healthy ones while there was significant decrease in the levels of albumin and A/G ratio. |