الفهرس | Only 14 pages are availabe for public view |
Abstract Part 1: A novel series of interesting 6,8-dicyanopyrido[1,2-a]thieno[3,2-e]pyrimidine-2-carboxylate derivatives were prepared via the versatile readily accessible 2-cyano-N-(thiophen-2-yl)acetamide with arylidenemalononitriles in pyridine containing piperidine. The structures of the prepared compounds were elucidated by several spectral tools as well as elemental analysis. Biological screening of the tested compounds as antibacterial agents was also studied. Part 2: A novel series of interesting pyrido[2,1-a]isoquinolines in the form of mono, bis and spirocyclic-oxindoles were prepared via the reaction of readily accessible 2-(6,7-dimethoxy-3,4- dihydroisoquinolin-1-yl)acetonitrile with arylidenes in the presence of different catalysts. The structures of the prepared compounds were elucidated by several spectral tools as well as elemental analysis |